An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Ye Zhang, Kenian Chen, Steven A. Sloan, +14

Journal of Neuroscience

Spike mutation D614G alters SARS-CoV-2 fitness

Jessica A. Plante, Yang Liu, Jianying Liu, +19

Nature

Viral EvolutionViral PathogenesisVirologyViral Structural ProteinSystems Biology +3

Mesenchymal Stem Cells: Revisiting History, Concepts, and Assays

Paolo Bianco, Pamela Gehron Robey, Paul J. Simmons

Cell stem cell

Regenerative MedicineMesenchymal Stem CellsMedicineAdult Stem CellStem Cell Research +4

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

Uma Prabhakar, Hiroshi Maeda, Rakesh K. Jain, +7

Cancer Research

NanoparticlesWorkshop DiscussionsEngineeringBiomedical EngineeringEnhanced Permeability +16

Genetic analyses of diverse populations improves discovery for complex traits

Genevieve L. Wojcik, Mariaelisa Graff, Katherine K. Nishimura, +82

Nature

BiologyGenetic AnalysisGenetic DiversityGenotype-phenotype AssociationNatural Sciences +9

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/β-catenin signaling

Kendra S. Carmon, Xing Gong, Qiushi Lin, +2

Proceedings of the National Academy of Sciences

Stem Cell GrowthMolecular RegulationCellular PhysiologyTissue DevelopmentCell Regulation +19

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

Amit V. Khera, Mark Chaffin, Kaitlin H. Wade, +16

Cell

ObesityChildhood ObesityBody CompositionObesity TrajectoriesPolygenic Risk +6

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis

Bryan A. Johnson, Xuping Xie, Adam L. Bailey, +30

Nature

PathogenesisViral PathogenesisImmunologyVirologyMedicine +2

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function

Yingjun Zhao, Xilin Wu, Xiaoguang Li, +13

Neuron

Neurodegenerative DiseasesMicroglial FunctionMedicineImmunologyDegenerative Pathology +4

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Alexander G. Bick, Joshua S. Weinstock, Satish K. Nandakumar, +405

Nature

Genetic DisorderGeneticsHematologyInherited CausesChromosomal Rearrangement +1