Zachary Bowen

Insights into SCF ubiquitin ligases from the structure of the Skp1–Skp2 complex

Brenda A. Schulman, Andrea C. Carrano, Philip D. Jeffrey et al. · Nature · 2000 · 602 citations

Protein Function, Structural Bioinformatics, Scf Ubiquitin Ligases +5

Acat1 Knockdown Gene Therapy Decreases Amyloid-β in a Mouse Model of Alzheimer's Disease

Stephanie R Murphy, Catherine C.Y. Chang, Godwin Dogbevia et al. · Molecular Therapy · 2013 · 100 citations · Full text

Ad Mice, Therapeutics, Genetic Inactivation +18

Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage

Yohei Shibuya, Zhaoyang Niu, Elena Y. Bryleva et al. · Neurobiology of Aging · 2015 · 93 citations

Cell Autophagy, Mitophagy, Triple Transgenic Alzheimer +10