Elena Y. Bryleva

ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD

Elena Y. Bryleva, Maximillian A. Rogers, Catherine C.Y. Chang et al. · Proceedings of the National Academy of Sciences · 2010 · 202 citations · Full text

Inhibiting ACAT1/SOAT1 in Microglia Stimulates Autophagy-Mediated Lysosomal Proteolysis and Increases Aβ1–42 Clearance

Yohei Shibuya, Catherine C.Y. Chang, Li‐Hao Huang et al. · Journal of Neuroscience · 2014 · 104 citations · Full text

Immunology, Neurochemical Biomarkers, Neuroinflammation +23

Acat1 Knockdown Gene Therapy Decreases Amyloid-β in a Mouse Model of Alzheimer's Disease

Stephanie R Murphy, Catherine C.Y. Chang, Godwin Dogbevia et al. · Molecular Therapy · 2013 · 100 citations · Full text

Ad Mice, Therapeutics, Genetic Inactivation +18

Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage

Yohei Shibuya, Zhaoyang Niu, Elena Y. Bryleva et al. · Neurobiology of Aging · 2015 · 93 citations

Cell Autophagy, Mitophagy, Triple Transgenic Alzheimer +10

Altered Tryptophan Catabolism in Placentas From Women With Pre-eclampsia

Sarah A. Keaton, Patrick L. Heilman, Elena Y. Bryleva et al. · International Journal of Tryptophan Research · 2019 · 33 citations · Full text