Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function

Yasuhiro Nose, Byung‐Eun Kim, Dennis J. Thiele

Cell Metabolism

Intestinal Copper AbsorptionIron MetabolismMetalloproteinPhysiologyBioactive Metal +4

A Histidine-rich Cluster Mediates the Ubiquitination and Degradation of the Human Zinc Transporter, hZIP4, and Protects against Zinc Cytotoxicity

Xiaoqing Mao, Byung‐Eun Kim, Fudi Wang, +2

Journal of Biological Chemistry

Iron MetabolismImmunologyMolecular BiologyRedox BiologyCellular Physiology +19

Cardiac Copper Deficiency Activates a Systemic Signaling Mechanism that Communicates with the Copper Acquisition and Storage Organs

Byung‐Eun Kim, Michelle L. Turski, Yasuhiro Nose, +3

Cell Metabolism

Cardiac MuscleCardiomyopathyHeart FailureCardiac Copper DeficiencySystemic Signaling Mechanism +7

Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice

Liam M. Guthrie, Shivatheja Soma, Sai Yuan, +14

Science

The Mammalian Zip5 Protein Is a Zinc Transporter That Localizes to the Basolateral Surface of Polarized Cells

Fudi Wang, Byung‐Eun Kim, Michael J. Petris, +1

Journal of Biological Chemistry

Molecular BiologyCellular PhysiologyPolarized CellsMammalian Zip5 ProteinZinc Uptake Transporter +20

Zn2+-stimulated Endocytosis of the mZIP4 Zinc Transporter Regulates Its Location at the Plasma Membrane

Byung‐Eun Kim, Fudi Wang, Jodi Dufner‐Beattie, +3

Journal of Biological Chemistry

Ctr1 Is an Apical Copper Transporter in Mammalian Intestinal Epithelial Cells in Vivo That Is Controlled at the Level of Protein Stability

Yasuhiro Nose, L. Kent Wood, Byung‐Eun Kim, +4

Journal of Biological Chemistry

GastroenterologyDigestive TractCellular PhysiologyOxidative StressApical Copper Transporter +22

Copper-regulated Trafficking of the Menkes Disease Copper ATPase Is Associated with Formation of a Phosphorylated Catalytic Intermediate

Michael J. Petris, Ilia Voskoboinik, Michael A. Cater, +6

Journal of Biological Chemistry

Zinc-stimulated Endocytosis Controls Activity of the Mouse ZIP1 and ZIP3 Zinc Uptake Transporters

Fudi Wang, Jodi Dufner‐Beattie, Byung‐Eun Kim, +3

Journal of Biological Chemistry

Elesclomol restores mitochondrial function in genetic models of copper deficiency

Shivatheja Soma, Andrew J. Latimer, Haarin Chun, +9

Proceedings of the National Academy of Sciences

GeneticsMolecular BiologyMolecular GeneticsFatal Mitochondrial DiseaseChemical Biology +14