Cardiac Copper Deficiency Activates a Systemic Signaling Mechanism that Communicates with the Copper Acquisition and Storage Organs

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Elizabeta Nemeth, Marie S. Tuttle, Julie Powelson et al. · Science · 2004 · 4.8K citations

Medicine, Cell Biology, Physiology +17

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ERT and Cre-ERT2 recombinases

Arup K. Indra, Xavier Warot, Jacques Brocard et al. · Nucleic Acids Research · 1999 · 763 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Temporally Regulated and Tissue-Specific Gene Manipulations in the Adult and Embryonic Heart Using a Tamoxifen-Inducible Cre Protein

Dawinder S. Sohal, Mai P. Nghiem, Michael A. Crackower et al. · Circulation Research · 2001 · 712 citations

Life Sciences, Genetics, Molecular Genetics +14

CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life

Sailaja Elchuri, Terry D. Oberley, Wenbo Qi et al. · Oncogene · 2004 · 665 citations

Pharmacy, Biochemistry, Toxicology +14

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

Ramtin Agah, Peter Frenkel, Brent A. French et al. · Journal of Clinical Investigation · 1997 · 615 citations · Full text

Life Sciences, Genetics, Molecular Biology +11