Concepedia

Copper Homeostasis

Copper Homeostasis is a biological regulatory mechanism that maintains optimal intracellular copper concentrations by balancing uptake, distribution, utilization, and efflux to prevent toxicity while ensuring proper function of cuproproteins.

2.8K

Publications

174.6K

Citations

10.4K

Authors

2.4K

Institutions

Publications per year

2017–2026

673

Parents

Publications

2.8K

Copper induces cell death by targeting lipoylated TCA cycle proteins

Peter Tsvetkov, Shannon Coy, Boryana Petrova et al. · Science · 2022 · 4.7K citations · Full text

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Undetectable Intracellular Free Copper: The Requirement of a Copper Chaperone for Superoxide Dismutase

Tracey Rae, Paul J. Schmidt, Robert A. Pufahl et al. · Science · 1999 · 1.6K citations

, , +13

Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper–transporting ATPase

Chris D. Vulpe, Barbara Levinson, Susan Whitney et al. · Nature Genetics · 1993 · 1.4K citations

, , +8

Copper: An essential metal in biology

Richard A. Festa, Dennis J. Thiele · Current Biology · 2011 · 1.2K citations · Full text

, , +12

The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity

Lee Macomber, James A. Imlay · Proceedings of the National Academy of Sciences · 2009 · 1.1K citations · Full text

, , +17

1–5 of 2.8K

Authors

10.4K

  1. DJ
    Dennis J. Thiele

    University of Michigan, United States

    48 publications · 8.9K citations

    39

    h-index

  2. JR
    Joseph R. Prohaska

    University of Minnesota, Duluth, United States

    34 publications · 2.8K citations

    25

    h-index

  3. SM
    Sabeeha Merchant

    University of California, Los Angeles, United States

    27 publications · 2.6K citations

    24

    h-index

  4. JD
    Jonathan D. Gitlin

    Mallinckrodt (United States), United States

    25 publications · 4.6K citations

    23

    h-index

  5. SL
    Svetlana Lutsenko

    Johns Hopkins University, United States

    25 publications · 6.9K citations

    22

    h-index

1–5 of 10.4K

Institutions

2.4K

  1. The University of Melbourne

    Melbourne, Australia

    42 h-index

    245 publications

    18K citations

  2. University of Michigan

    Ann Arbor, United States

    32 h-index

    112 publications

    20.1K citations

  3. Johns Hopkins University

    Baltimore, United States

    32 h-index

    137 publications

    27.6K citations

  4. University of California, Berkeley

    Berkeley, United States

    32 h-index

    135 publications

    18.6K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    32 h-index

    292 publications

    20.7K citations

  6. Duke University

    Durham, United States

    30 h-index

    78 publications

    10.3K citations

  7. Grand Forks Human Nutrition Research Center

    Grand Forks, United States

    27 h-index

    96 publications

    5.3K citations

  8. University of California, Los Angeles

    Los Angeles, United States

    27 h-index

    126 publications

    14.2K citations

1–8 of 2.4K

Venues

  1. Journal of Biological Chemistry

    JBC · 153 publications · 19.5K citations

    83

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 54 publications · 10.7K citations

    46

    h-index

  3. Journal of Nutrition

    JN · 79 publications · 3.7K citations

    39

    h-index

  4. Metallomics

    57 publications · 2.4K citations

    29

    h-index

  5. PubMed

    Repository · 53 publications · 2.1K citations

    26

    h-index

1–5