Shivatheja Soma

Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice

Liam M. Guthrie, Shivatheja Soma, Sai Yuan et al. · Science · 2020 · 188 citations · Full text

Life Sciences, Biochemistry, Neurology +17

FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery

Mohammad Zulkifli, Amy N. Spelbring, Yuteng Zhang et al. · Proceedings of the National Academy of Sciences · 2023 · 138 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Elesclomol restores mitochondrial function in genetic models of copper deficiency

Shivatheja Soma, Andrew J. Latimer, Haarin Chun et al. · Proceedings of the National Academy of Sciences · 2018 · 104 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Mitochondrial disease genes<i>COA6</i>,<i>COX6B</i>and<i>SCO2</i>have overlapping roles in COX2 biogenesis

Alok Ghosh, Anthony T. Pratt, Shivatheja Soma et al. · Human Molecular Genetics · 2015 · 55 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase

Shivatheja Soma, Marcos N. Morgada, Mandar T. Naik et al. · Cell Reports · 2019 · 53 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17