Makoto Ishii

Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity

Makoto Ishii, Fei Hong, Jeffrey M. Friedman · Proceedings of the National Academy of Sciences · 2003 · 117 citations · Full text

Fasting-Induced Hypothermia and Reduced Energy Production in Mice Lacking Acetyl-CoA Synthetase 2

Iori Sakakibara, Takahiro Fujino, Makoto Ishii et al. · Cell Metabolism · 2009 · 110 citations · Full text

Energy Homeostasis, Energy Metabolism, Biochemistry +10

Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract

Risako Kon, Nobutomo Ikarashi, Chika Nagoya et al. · Journal of Ethnopharmacology · 2014 · 107 citations

Inflammation, Rhubarb Extract, Anti-inflammatory +8

Transgenic Mice Overexpressing Amyloid Precursor Protein Exhibit Early Metabolic Deficits and a Pathologically Low Leptin State Associated with Hypothalamic Dysfunction in Arcuate Neuropeptide Y Neurons

Makoto Ishii, G. Wang, Gianfranco Racchumi et al. · Journal of Neuroscience · 2014 · 99 citations · Full text

The laxative effect of bisacodyl is attributable to decreased aquaporin-3 expression in the colon induced by increased PGE₂secretion from macrophages

Nobutomo Ikarashi, Kohta Baba, Takashi Ushiki et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2011 · 95 citations