Nobutomo Ikarashi

Anti‐Obesity and Anti‐Diabetic Effects of Acacia Polyphenol in Obese Diabetic KKAy Mice Fed High‐Fat Diet

Nobutomo Ikarashi, Takahiro Toda, Takehiro Okaniwa et al. · Evidence-based Complementary and Alternative Medicine · 2010 · 123 citations · Full text

Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract

Risako Kon, Nobutomo Ikarashi, Chika Nagoya et al. · Journal of Ethnopharmacology · 2014 · 107 citations

Inflammation, Rhubarb Extract, Anti-inflammatory +8

Intestinal flora induces the expression of Cyp3a in the mouse liver

Tsuguto Toda, Noriyuki Saito, Nobutomo Ikarashi et al. · Xenobiotica · 2009 · 100 citations

The laxative effect of bisacodyl is attributable to decreased aquaporin-3 expression in the colon induced by increased PGE₂secretion from macrophages

Nobutomo Ikarashi, Kohta Baba, Takashi Ushiki et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2011 · 95 citations

Morphine-Induced Constipation Develops With Increased Aquaporin-3 Expression in the Colon via Increased Serotonin Secretion

Risako Kon, Nobutomo Ikarashi, Akio Hayakawa et al. · Toxicological Sciences · 2015 · 93 citations

Morphine-induced Constipation, Gastrointestinal Pharmacology, Oral Morphine Administration +19