John R. Springer

The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life

Jane L. Wang, David C. Limburg, Matthew J. Graneto et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 335 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation

Graciela B. Arhancet, Daniel P. Walker, Sue Metz et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 48 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design

Daniel P. Walker, Graciela B. Arhancet, Hwang‐Fun Lu et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Aminopyrazole Carboxamide Bruton’s Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning

Mark E. Schnute, Stephen Benoit, Ingrid P. Buchler et al. · ACS Medicinal Chemistry Letters · 2018 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Process Research, Development, and Pilot-Plant Preparation of Clofencet, a Novel Wheat Hybridizing Agent:  Lewis Acid-Catalyzed Reaction of Ethyl Diazoacetate with 4-Chlorophenyl Hydrazonoacetaldehyde

Jerry D. Clark, Jerald D. Heise, Ajit S. Shah et al. · Organic Process Research & Development · 2004 · 24 citations

Natural Sciences, Chemistry, Drug Discovery +10