Sadayappan V. Rahavendran

Discovery of (<i>R</i>)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-<i>a</i>]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor

Hui Li, John Tatlock, Angelica Linton et al. · Journal of Medicinal Chemistry · 2009 · 118 citations · Full text

Viral Polymerase Structure, Pharmacotherapy, Antiviral Drug +16

Preclinical Characterization of PF-00868554, a Potent Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase

Stephanie T. Shi, Koleen J. Herlihy, Joanne P. Graham et al. · Antimicrobial Agents and Chemotherapy · 2009 · 75 citations · Full text

Genotype 1A, Immunology, Molecular Biology +18

Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers

Yazdi K. Pithavala, Warren Tong, Janessa Mount et al. · Investigational New Drugs · 2010 · 61 citations · Full text

Influence of mild and moderate hepatic impairment on axitinib pharmacokinetics

Michael A. Tortorici, Melvin Toh, Sadayappan V. Rahavendran et al. · Investigational New Drugs · 2010 · 55 citations · Full text

Azaindole Hydroxamic Acids are Potent HIV-1 Integrase Inhibitors

Michael Plewe, Scott L. Butler, Klaus Dress et al. · Journal of Medicinal Chemistry · 2009 · 53 citations · Full text

Hiv-1 In Inhibitors, Medicinal Chemistry, Hiv-1 Integrase +15