Choong‐Ryoul Sihn

Interindividual variability in transgene mRNA and protein production following adeno-associated virus gene therapy for hemophilia A

Sylvia Fong, Bridget Yates, Choong‐Ryoul Sihn et al. · Nature Medicine · 2022 · 106 citations · Full text

Gene Therapy with BMN 270 Results in Therapeutic Levels of FVIII in Mice and Primates and Normalization of Bleeding in Hemophilic Mice

Stuart Bunting, Lening Zhang, Lin Xie et al. · Molecular Therapy · 2017 · 72 citations · Full text

Vector genome loss and epigenetic modifications mediate decline in transgene expression of AAV5 vectors produced in mammalian and insect cells

Britta Handyside, Ashrafali Mohamed Ismail, Lening Zhang et al. · Molecular Therapy · 2022 · 46 citations · Full text

Induction of ER Stress by an AAV5 BDD FVIII Construct Is Dependent on the Strength of the Hepatic-Specific Promoter

Sylvia Fong, Britta Handyside, Choong‐Ryoul Sihn et al. · Molecular Therapy — Methods & Clinical Development · 2020 · 42 citations · Full text

Hepatic-specific Promoter, Adeno-associated Virus 5, Immunology +18

Cooperativity of K _v 7.4 channels confers ultrafast electromechanical sensitivity and emergent properties in cochlear outer hair cells

Maria C. Perez-Flores, Jeong H. Lee, Seojin Park et al. · Science Advances · 2020 · 35 citations · Full text