Concepedia

Author

Britta Handyside

BioMarin (United States)ORCID

Also Known As

B. Handyside, Britta Handyside

17

Publications

282

Citations

8

H-Index

12

Concepts

All Affiliations

BioMarin (United States)St. Jude Children's Research Hospital
BH

About

Britta Handyside is an author at BioMarin (United States) specializing in cell signaling, liver physiology, and gene expression.

Top Concepts

#ConceptH-IndexPublicationsCitations

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Medicine

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2

Cell Biology

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3

Hepatology

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42

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Immunology

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Pathology

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Britta Handyside

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8

Publications

266

Citations

8

H-Index

YearCitations

Gene Therapy with BMN 270 Results in Therapeutic Levels of FVIII in Mice and Primates and Normalization of Bleeding in Hemophilic Mice

Stuart Bunting, Lening Zhang, Lin Xie,

Molecular Therapy

2017

72

Vector genome loss and epigenetic modifications mediate decline in transgene expression of AAV5 vectors produced in mammalian and insect cells

Britta Handyside, Ashrafali Mohamed Ismail, Lening Zhang,

Molecular Therapy

2022

46

Induction of ER Stress by an AAV5 BDD FVIII Construct Is Dependent on the Strength of the Hepatic-Specific Promoter

Sylvia Fong, Britta Handyside, Choong‐Ryoul Sihn,

Molecular Therapy — Methods & Clinical Development

2020

42

Intracerebroventricular enzyme replacement therapy with β-galactosidase reverses brain pathologies due to GM1 gangliosidosis in mice

Joseph C. Chen, Amanda Luu, Nathan Wise,

Journal of Biological Chemistry

2019

39

Molecular analysis of AAV5-hFVIII-SQ vector-genome-processing kinetics in transduced mouse and nonhuman primate livers

Choong‐Ryoul Sihn, Britta Handyside, Su Liu,

Molecular Therapy — Methods & Clinical Development

2021

31

Intermittent enzyme replacement therapy with recombinant human β-galactosidase prevents neuraminidase 1 deficiency

Amanda Luu, Cara Wong, Vishal Agrawal,

Journal of Biological Chemistry

2020

13

Application of in-vitro-cultured primary hepatocytes to evaluate species translatability and AAV transduction mechanisms of action

Su Liu, Lisa Razon, Olivia Ritchie,

Molecular Therapy — Methods & Clinical Development

2022

13

Prednisolone Does Not Regulate Factor VIII Expression in Mice Receiving AAV5-hFVIII-SQ: Valoctocogene Roxaparvovec

Lening Zhang, Britta Handyside, Ryan Murphy,

Molecular Therapy — Methods & Clinical Development

2019

10

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