Bridget Yates

Interindividual variability in transgene mRNA and protein production following adeno-associated virus gene therapy for hemophilia A

Sylvia Fong, Bridget Yates, Choong‐Ryoul Sihn et al. · Nature Medicine · 2022 · 106 citations · Full text

Strategy to detect pre-existing immunity to AAV gene therapy

Lillian Falese, Krystal Sandza, Bridget Yates et al. · Gene Therapy · 2017 · 97 citations · Full text

Gene Therapy with BMN 270 Results in Therapeutic Levels of FVIII in Mice and Primates and Normalization of Bleeding in Hemophilic Mice

Stuart Bunting, Lening Zhang, Lin Xie et al. · Molecular Therapy · 2017 · 72 citations · Full text

A Genome-Scale RNA–Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease

John P. Miller, Bridget Yates, Ismael Al‐Ramahi et al. · PLoS Genetics · 2012 · 49 citations · Full text

Engineering, Mitochondrial Dysfunction, Genetics +21

Vector genome loss and epigenetic modifications mediate decline in transgene expression of AAV5 vectors produced in mammalian and insect cells

Britta Handyside, Ashrafali Mohamed Ismail, Lening Zhang et al. · Molecular Therapy · 2022 · 46 citations · Full text