Nathan T. Ross

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

Rashid Deane, Itender Singh, Abhay P. Sagare et al. · Journal of Clinical Investigation · 2012 · 602 citations · Full text

Social Sciences, Neuroinflammation, Alzheimer's Disease +17

An Aldol-Based Build/Couple/Pair Strategy for the Synthesis of Medium- and Large-Sized Rings: Discovery of Macrocyclic Histone Deacetylase Inhibitors

Lisa A. Marcaurelle, Eamon Comer, Sivaraman Dandapani et al. · Journal of the American Chemical Society · 2010 · 212 citations · Full text

Combinatorial Chemistry, Aldol-based Build/couple/pair, Stereochemical Dependencies +19

A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells

Michel Weïwer, James Spoonamore, Jingqiang Wei et al. · ACS Medicinal Chemistry Letters · 2012 · 138 citations · Full text

Kinase-selectivity Profiles, Cell Death, Cancer Biology +21

Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation

Cheryl Carson, Pichai Raman, Jennifer Tullai et al. · PLoS ONE · 2015 · 108 citations · Full text

Trpc4/c5 Cation Channels, Trpc4 Channel, Cancer Biology +16

Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti‐Cancer Properties

Philipp Krastel, Silvio Roggo, Markus Schirle et al. · Angewandte Chemie International Edition · 2015 · 106 citations