Mandheer Wadhwa

Downstream of Mutant KRAS, the Transcription Regulator YAP Is Essential for Neoplastic Progression to Pancreatic Ductal Adenocarcinoma

Weiying Zhang, Nivedita Nandakumar, Yuhao Shi et al. · Science Signaling · 2014 · 358 citations · Full text

Tumor Biology, Transcriptional Regulation, Pdac Progression +15

DNA damage by oxidative stress: Measurement strategies for two genomes

Claudia P. González-Hunt, Mandheer Wadhwa, Laurie H. Sanders · Current Opinion in Toxicology · 2018 · 122 citations

Reductive Stress, Chromatin, Genome Instability +13

Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7

Colleen A. Stoyas, David D. Bushart, Paweł M. Świtoński et al. · Neuron · 2019 · 81 citations · Full text

Neurodegenerative Diseases, Achieve Neuroprotection, Neuropharmacology +8

Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients

Craig L. Bennett, Somasish Ghosh Dastidar, Shuo‐Chien Ling et al. · Acta Neuropathologica · 2018 · 61 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Genetics +10

Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression

Yuhao Shi, Saumya Bollam, Shannon M. White et al. · Developmental Cell · 2016 · 35 citations · Full text

Limit Cell-cycle Progression, Genome Instability, Cell Regulation +8