Sung‐Hou Kim

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

James Tsai, John Tayu Lee, Weiru Wang et al. · Proceedings of the National Academy of Sciences · 2008 · 1.3K citations · Full text

Medicine, Oncology, Pharmacology +15

Molecular Switch for Signal Transduction: Structural Differences Between Active and Inactive Forms of Protooncogenic <i>ras</i> Proteins

Michael V. Milburn, Liang Tong, Abraham M. deVos et al. · Science · 1990 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +17

Crystal structure of cyclin-dependent kinase 2

Hendrik L. De Bondt, Jody Rosenblatt, Jarmila Jancarik et al. · Nature · 1993 · 968 citations

Life Sciences, Cell Biology, Molecular Biology +14

Crystal structure of a small heat-shock protein

Kyeong Kyu Kim, Rosalind Kim, Sung‐Hou Kim · Nature · 1998 · 892 citations

Life Sciences, Biochemistry, Biophysics +12

Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors

Nathanael S. Gray, Lisa Wodicka, A.M.W.H. Thunnissen et al. · Science · 1998 · 808 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +15