Concepedia

Janina Niggenaber

JN

6

Publications

172

Citations

6

H-Index

2019

Active since

Affiliations

TU Dortmund University(Current)

Lead Discovery Center (Germany)

German Cancer Research Center

Deutschen Konsortium für Translationale Krebsforschung

Stellenbosch University

Janina Niggenaber is an author at TU Dortmund University specializing in drug discovery, molecular biology, and medicine.

ORCID

Top concepts

Publications per year

2019–2024

6

Publications

6

Complex Crystal Structures of EGFR with Third-Generation Kinase Inhibitors and Simultaneously Bound Allosteric Ligands

Janina Niggenaber, Leonie Heyden, Tobias Grabe et al. · ACS Medicinal Chemistry Letters · 2020 · 49 citations · Full text

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Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S

Jonas Lategahn, Marina Keul, Philip Klövekorn et al. · Chemical Science · 2019 · 48 citations · Full text

Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors

Jonas Lategahn, Hannah L. Tumbrink, Carsten Schultz‐Fademrecht et al. · Journal of Medicinal Chemistry · 2022 · 23 citations

Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA

Alina Teuber, Tom Schulz, B. S. Fletcher et al. · Nature Communications · 2024 · 20 citations · Full text

Targeting Her2-insYVMA with Covalent Inhibitors—A Focused Compound Screening and Structure-Based Design Approach

Jonas Lategahn, Julia Hardick, Tobias Grabe et al. · Journal of Medicinal Chemistry · 2020 · 17 citations · Full text

, , +19

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