Concepedia

Marina Keul

MK

Statistics

Publications

13

Citations

724

H-Index

13

Active since

2015

Affiliations

TU Dortmund University(Current)

Lead Discovery Center (Germany)

Deutsches Konsortium für Translationale Krebsforschung

University Hospital Cologne

University of Cologne

Marina Keul is an author at TU Dortmund University specializing in pharmacology, drug discovery, and molecular oncology.

ORCID

Publications per year

2015–2022

13

Publications

13

Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors

Jana Fassunke, Fabienne Müller, Marina Keul et al. · Nature Communications · 2018 · 139 citations · Full text

, , +15

Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach

Julian Engel, André Richters, Matthäus Getlik et al. · Journal of Medicinal Chemistry · 2015 · 112 citations · Full text

, , +16

Trisubstituted Pyridinylimidazoles as Potent Inhibitors of the Clinically Resistant L858R/T790M/C797S EGFR Mutant: Targeting of Both Hydrophobic Regions and the Phosphate Binding Site

Marcel Günther, Jonas Lategahn, Michael Juchum et al. · Journal of Medicinal Chemistry · 2017 · 107 citations · Full text

, , +14

Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors

Dennis Plenker, M Riedel, Johannes Brägelmann et al. · Science Translational Medicine · 2017 · 64 citations · Full text

, , +12

Insight into the Inhibition of Drug‐Resistant Mutants of the Receptor Tyrosine Kinase EGFR

Julian Engel, Christian Becker, Jonas Lategahn et al. · Angewandte Chemie International Edition · 2016 · 63 citations

, , +15

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