Michael Juchum - Concepedia

Author

Michael Juchum

University of Tübingen

Also Known As

Juchum, Michael, Michael Juchum

Publications

474

Citations

H-Index

Concepts

All Affiliations

University of Tübingen Heidelberg University German Cancer Research Center

About

Michael Juchum is an author at University of Tübingen specializing in drug discovery, medicine, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	254
2	Natural Sciences	3	3	137
3	Chemical Biology	3	3	137
4	Biochemistry	2	2	115
5	Biomolecular Engineering	2	2	37

Michael Juchum

Publications

336

Citations

H-Index

Page 1

	Year	Citations
Lung Cancer: EGFR Inhibitors with Low Nanomolar Activity against a Therapy‐Resistant L858R/T790M/C797S Mutant Marcel Günther, Michael Juchum, Gerhard Kelter, Angewandte Chemie International Edition Drug TargetingOncologyNovel TherapyTumor MicroenvironmentMedicine	2016	102
Trisubstituted Pyridinylimidazoles as Potent Inhibitors of the Clinically Resistant L858R/T790M/C797S EGFR Mutant: Targeting of Both Hydrophobic Regions and the Phosphate Binding Site Marcel Günther, Jonas Lategahn, Michael Juchum, Journal of Medicinal Chemistry Drug TargetBoth Hydrophobic RegionsChemical BiologyMutant Egfr InhibitionPharmaceutical Chemistry	2017	102
Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping Michael Juchum, Marcel Günther, Eva Döring, Journal of Medicinal Chemistry	2017	82
Design and synthesis of 1H-pyrazolo[3,4-b]pyridines targeting mitogen-activated protein kinase kinase 4 (MKK4) - A promising target for liver regeneration Bent Pfaffenrot, Philip Klövekorn, Michael Juchum, European Journal of Medicinal Chemistry Medicinal ChemistryNatural SciencesDrug DiscoveryMedicineLiver Regeneration	2021	22
From off-to on-target: New BRAF-inhibitor-template-derived compounds selectively targeting mitogen activated protein kinase kinase 4 (MKK4) Philip Klövekorn, Bent Pfaffenrot, Michael Juchum, European Journal of Medicinal Chemistry New Braf-inhibitor-template-derivedMedicinal ChemistryDrug TargetSignal TransductionDrug Targeting	2020	15
Design and synthesis of novel fluorescently labeled analogs of vemurafenib targeting MKK4 Theresa Kircher, Tatu Pantsar, Andreas Oder, European Journal of Medicinal Chemistry Medicinal ChemistryDrug TargetDrug TargetingPharmaceutical ScienceBiochemistry	2020	13

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