Hannah L. Tumbrink

Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors

Jana Fassunke, Fabienne Müller, Marina Keul et al. · Nature Communications · 2018 · 139 citations · Full text

Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes

Christina M. Bebber, Emily Thomas, Jenny Stroh et al. · Nature Communications · 2021 · 137 citations · Full text

Trisubstituted Pyridinylimidazoles as Potent Inhibitors of the Clinically Resistant L858R/T790M/C797S EGFR Mutant: Targeting of Both Hydrophobic Regions and the Phosphate Binding Site

Marcel Günther, Jonas Lategahn, Michael Juchum et al. · Journal of Medicinal Chemistry · 2017 · 102 citations · Full text

Drug Target, Both Hydrophobic Regions, Chemical Biology +21

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer

Marcel A. Dammert, Johannes Brägelmann, Rachelle R. Olsen et al. · Nature Communications · 2019 · 83 citations · Full text

Indazole-Based Covalent Inhibitors To Target Drug-Resistant Epidermal Growth Factor Receptor

Stefano Tomassi, Jonas Lategahn, Julian Engel et al. · Journal of Medicinal Chemistry · 2017 · 55 citations · Full text

Drug Target, Pharmacotherapy, Dermatology +16