Concepedia

Samuel N. Young

SN

32

Publications

4.5K

Citations

25

H-Index

2012

Active since

Affiliations

Walter and Eliza Hall Institute of Medical Research(Current)

The University of Melbourne

Monash University

The Royal Melbourne Hospital

University of Canterbury

Samuel N. Young is an author at Walter and Eliza Hall Institute of Medical Research specializing in medicine, cell signaling, and cell biology.

ORCID

Top concepts

Publications per year

2012–2024

32

Publications

32

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

, , +14

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Joanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet et al. · Proceedings of the National Academy of Sciences · 2014 · 581 citations · Full text

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis

André L. Samson, Ying Zhang, Niall D. Geoghegan et al. · Nature Communications · 2020 · 335 citations · Full text

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties

James M. Murphy, Qingwei Zhang, Samuel N. Young et al. · Biochemical Journal · 2013 · 280 citations · Full text

, , +25

Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity

Jeffrey J. Babon, Nadia J. Kershaw, James M. Murphy et al. · Immunity · 2012 · 256 citations · Full text

, , +13

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