Annamaria Braendli-Baiocco

Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling

Annie Moisan, Marcel Gubler, Jitao David Zhang et al. · Molecular Therapy — Nucleic Acids · 2016 · 33 citations · Full text

Urology, Nephrotoxic Antisense Drugs, Preclinical Drug Evaluation +15

Characterizing Adversity of Lysosomal Accumulation in Nonclinical Toxicity Studies: Results from the 5th ESTP International Expert Workshop

Barbara Lenz, Annamaria Braendli-Baiocco, Jeffery A. Engelhardt et al. · Toxicologic Pathology · 2018 · 30 citations · Full text

Biochemistry, Nonclinical Toxicity Studies, Medicine +15

Monitoring Cyp2b10 mRNA expression at cessation of 2-year carcinogenesis bioassay in mouse liver provides evidence for a carcinogenic mechanism devoid of human relevance: The dalcetrapib experience

J.C. Hoflack, Lutz Mueller, Stephen Fowler et al. · Toxicology and Applied Pharmacology · 2012 · 16 citations

2-Year Carcinogenesis Bioassay, Hepatocellular Carcinoma, Medicine +13

GalNAc Conjugation Attenuates the Cytotoxicity of Antisense Oligonucleotide Drugs in Renal Tubular Cells

Sabine Sewing, Marcel Gubler, Régine Gérard et al. · Molecular Therapy — Nucleic Acids · 2018 · 16 citations · Full text

Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats

F. Romero-Palomo, Matthias Festag, Barbara Lenz et al. · Toxicologic Pathology · 2021 · 16 citations

Immunology, Cell Death, Toxicological Mechanism +18