Stephen Fowler

Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling

Nicole A. Kratochwil, Christophe Meille, Stephen Fowler et al. · The AAPS Journal · 2017 · 107 citations · Full text

Fatty Liver Disease, Physiologically-based Pharmacokinetic Modeling, Metabolic Syndrome +25

Minimizing DILI risk in drug discovery — A screening tool for drug candidates

Simone Schadt, Silke Simon, Stefan Kustermann et al. · Toxicology in Vitro · 2015 · 88 citations

Drug Target, Hit Identification, Drug Candidates +8

Characterization of the Ontogeny of Hepatic UDP‐Glucuronosyltransferase Enzymes Based on Glucuronidation Activity Measured in Human Liver Microsomes

Justine Badée, NaHong Qiu, Abby C. Collier et al. · The Journal of Clinical Pharmacology · 2019 · 64 citations

A UGT2B10 Splicing Polymorphism Common in African Populations May Greatly Increase Drug Exposure

Stephen Fowler, Heidemarie Kletzl, Moshe Finel et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 61 citations

Exploration and application of a liver-on-a-chip device in combination with modelling and simulation for quantitative drug metabolism studies

Luca Docci, Nicolò Milani, Thomas Ramp et al. · Lab on a Chip · 2022 · 61 citations · Full text