Stephen Fowler

Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling

Nicole A. Kratochwil, Christophe Meille, Stephen Fowler et al. · The AAPS Journal · 2017 · 109 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Minimizing DILI risk in drug discovery — A screening tool for drug candidates

Simone Schadt, Silke Simon, Stefan Kustermann et al. · Toxicology in Vitro · 2015 · 88 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Characterization of the Ontogeny of Hepatic UDP‐Glucuronosyltransferase Enzymes Based on Glucuronidation Activity Measured in Human Liver Microsomes

Justine Badée, NaHong Qiu, Abby C. Collier et al. · The Journal of Clinical Pharmacology · 2019 · 77 citations

Pharmacy, Biochemistry, Pharmacokinetics +16

Application of a gut–liver-on-a-chip device and mechanistic modelling to the quantitative <i>in vitro</i> pharmacokinetic study of mycophenolate mofetil

Nicolò Milani, Neil Parrott, Daniela Ortiz Franyuti et al. · Lab on a Chip · 2022 · 67 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Exploration and application of a liver-on-a-chip device in combination with modelling and simulation for quantitative drug metabolism studies

Luca Docci, Nicolò Milani, Thomas Ramp et al. · Lab on a Chip · 2022 · 64 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +17