Lutz Mueller

Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( <i>SMN2</i> ) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)

Hasane Ratni, Martin Ebeling, John D. Baird et al. · Journal of Medicinal Chemistry · 2018 · 520 citations · Full text

Medicine, Neurology, Pharmacology +14

Risdiplam distributes and increases <scp>SMN</scp> protein in both the central nervous system and peripheral organs

Agnès Poirier, Marla Weetall, Katja Heinig et al. · Pharmacology Research & Perspectives · 2018 · 169 citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy

Hasane Ratni, Gary M. Karp, Marla Weetall et al. · Journal of Medicinal Chemistry · 2016 · 113 citations

Life Sciences, Molecular Biology, Neuroscience +14

Experimental validation of a commercial 3D dose verification system for intensity-modulated arc therapies

Ramesh Boggula, Friedlieb Lorenz, Lutz Mueller et al. · Physics in Medicine and Biology · 2010 · 62 citations · Full text

Medicine, Radiation Oncology, Radiation Dosimetry +16

Structure–activity considerations and in vitro approaches to assess the genotoxicity of 19 methane-, benzene- and toluenesulfonic acid esters

Susanne Glowienke, Wilfried Frieauff, Thomas Allmendinger et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2004 · 57 citations

Pharmacy, Chemistry, Toxicology +13