Thomas Gaj

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

D. Gowanlock R. Tervo, Bum-Yeol Hwang, Sarada Viswanathan et al. · Neuron · 2016 · 1.3K citations · Full text

Projection Neurons, Engineering, Neuroengineering +8

Targeted gene knockout by direct delivery of zinc-finger nuclease proteins

Thomas Gaj, Jing Guo, Yoshio Kato et al. · Nature Methods · 2012 · 303 citations

Engineering, Genome Surgery, Genetic Engineering +7

Directed Evolution of an Enhanced and Highly Efficient FokI Cleavage Domain for Zinc Finger Nucleases

Jing Guo, Thomas Gaj, Carlos F. Barbas · Journal of Molecular Biology · 2010 · 201 citations

Biochemistry, Protein Assembly, Natural Sciences +6

Cell-Penetrating Peptide-Mediated Delivery of TALEN Proteins via Bioconjugation for Genome Engineering

Jia Liu, Thomas Gaj, James T Patterson et al. · PLoS ONE · 2014 · 149 citations · Full text

Engineering, Peptide Engineering, Molecular Biology +24

A Hypothalamic Switch for REM and Non-REM Sleep

Kai-Siang Chen, Min Xu, Zhe Zhang et al. · Neuron · 2018 · 148 citations · Full text

Sleep Disorders, Sleep, Sleep Medicine +12