Spatial partitioning of the regulatory landscape of the X-inactivation centre

Elphège P. Nora, Bryan R. Lajoie, Edda G. Schulz, +12

Nature

BiologySystems BiologyDevelopmental BiologyCell DivisionSpatial Partitioning +5

HiC-Pro: an optimized and flexible pipeline for Hi-C data processing

Nicolas Servant, Nelle Varoquaux, Bryan R. Lajoie, +6

Genome biology

EngineeringGeneticsComputer ArchitectureGenomicsHic-pro Maps Reads +21

A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis

Marie‐Agnès Dillies, Andréa Rau, Julie Aubert, +16

Briefings in Bioinformatics

EngineeringGeneticsTranscriptomics TechnologyGenomicsHigh Throughput Sequencing +19

Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial

Christophe Le Tourneau, Jean-Pierre Delord, Anthony Gonçalvès, +20

The Lancet Oncology

Advanced CancerDrug TargetingOncologyMedicineVersus Conventional Therapy +10

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

Elisabetta Volpe, Nicolas Servant, Raphaël Zollinger, +4

Nature Immunology

InflammationCytokineInterleukin 23Immune RegulationImmunology +8

Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure

María Elena Fernández-Sánchez, Sandrine Barbier, Joanne Whitehead, +19

Nature

MechanobiologyTumorigenic β-Catenin PathwayTumour Growth PressureMechanical InductionCell-matrix Interaction +8

LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation

Jennifer Chow, Constance Ciaudo, Melissa Fazzari, +10

Cell

ChromatinChromatin StructureChromatin RemodelingNatural SciencesGenetics +7

A druggable copper-signalling pathway that drives inflammation

Stéphanie Solier, Sebastian Müller, Tatiana Cañeque, +31

Nature

miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death

Lorenzo Galluzzi, Eugenia Morselli, Ilio Vitale, +13

Cancer Research

Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation

Serena Sanulli, N. Justin, Aurélie Teissandier, +14

Molecular Cell

Histone ModificationsMolecular RegulationEpigenetic ChangeMolecular BiologyCell Differentiation +19