Rasmus Hansen

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

Matthew R. Janes, Jingchuan Zhang, Lian‐Sheng Li et al. · Cell · 2018 · 1.1K citations · Full text

Kras Mutant Cancers, Medicine, Anti-cancer Agent +6

Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State

Matthew P. Patricelli, Matthew R. Janes, Lian‐Sheng Li et al. · Cancer Discovery · 2016 · 731 citations · Full text

Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism

Piro Lito, Martha Solomon, Lian‐Sheng Li et al. · Science · 2016 · 659 citations · Full text

Gtpase Activity, Signal Transduction, Biochemistry +15

Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling

Christopher Sellick, Rasmus Hansen, Gill Stephens et al. · Nature Protocols · 2011 · 246 citations

Biochemistry, Medicine, Bioanalysis +9

The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitors

Rasmus Hansen, Ulf Peters, Anjali Babbar et al. · Nature Structural & Molecular Biology · 2018 · 145 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +7