Matthew R. Janes

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Andrew C. Hsieh, Yi Liu, Merritt P. Edlind et al. · Nature · 2012 · 1.3K citations · Full text

Tumor Biology, Signal Transduction, Signaling Pathway +10

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

Matthew R. Janes, Jingchuan Zhang, Lian‐Sheng Li et al. · Cell · 2018 · 1.1K citations · Full text

Kras Mutant Cancers, Medicine, Anti-cancer Agent +6

Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State

Matthew P. Patricelli, Matthew R. Janes, Lian‐Sheng Li et al. · Cancer Discovery · 2016 · 731 citations · Full text

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

Matthew R. Janes, Jose J. Limon, Lomon So et al. · Nature Medicine · 2010 · 334 citations · Full text

Tumor Biology, Medicine, Malignant Blood Disorder +11

KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition

Sandra Misale, Jackson P. Fatherree, Eliane Cortez et al. · Clinical Cancer Research · 2018 · 253 citations