John Joosten

Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody–Drug Conjugate SYD985

Ronald C. Elgersma, Ruud G. E. Coumans, Tijl Huijbregts et al. · Molecular Pharmaceutics · 2015 · 214 citations · Full text

Molecular Biology, Duocarmycin 3B, Pharmaceutical Chemistry +16

Preclinical Profile of the HER2-Targeting ADC SYD983/SYD985: Introduction of a New Duocarmycin-Based Linker-Drug Platform

Wim H.A. Dokter, Ruud Ubink, Miranda van der Lee et al. · Molecular Cancer Therapeutics · 2014 · 156 citations · Full text

Drug Target, Immunology, Molecular Biology +18

High‐Yielding Microwave‐Assisted Synthesis of Triazole‐Linked Glycodendrimers by Copper‐Catalyzed [3+2] Cycloaddition

John Joosten, Niels T. H. Tholen, Fatna Ait el Maate et al. · European Journal of Organic Chemistry · 2005 · 107 citations

Chemical Engineering, Triazole‐linked Glycodendrimers, Engineering +13

Identification of the Smallest Structure Capable of Evoking Opsonophagocytic Antibodies against <i>Streptococcus pneumoniae</i> Type 14

Dodi Safari, Huberta A. T. Dekker, John Joosten et al. · Infection and Immunity · 2008 · 105 citations · Full text

Inhibition of <i>Streptococcus </i><i>s</i><i>uis</i> Adhesion by Dendritic Galabiose Compounds at Low Nanomolar Concentration

John Joosten, Vuokko Loimaranta, Chantal C.M. Appeldoorn et al. · Journal of Medicinal Chemistry · 2004 · 91 citations

Bioorganic Chemistry, Antibiotic Adjuvant, Bacteriology +17