J. P. G. Hermans

The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K

Elma Mons, Ineke D.C. Jansen, Jure Loboda et al. · Journal of the American Chemical Society · 2019 · 115 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15

ABCB1 Attenuates the Brain Penetration of the PARP Inhibitor AZD2461

Mark C. de Gooijer, Levi C.M. Buil, Ceren H. Çitirikkaya et al. · Molecular Pharmaceutics · 2018 · 25 citations

Medicine, Pharmacokinetics, Pharmacology +16

Synthesis of fragments of the capsular polysaccharide of <i>Haemophilus influenzae</i> type b: Part I. Preparation of suitably protected 1‐O‐β‐<i>D</i>‐ribofuranosyl‐<i>D</i>‐ribitol building blocks

J. P. G. Hermans, L. Poot, G. A. VAN DER MAREL et al. · Recueil des Travaux Chimiques des Pays-Bas · 1987 · 23 citations

Pharmacy, Chemistry, Microbiology +9

Chemical synthesis of diphosphorylated lipid a derivatives

C. A. A. VAN BOECKEL, J. P. G. Hermans, Pieter Westerduin et al. · Tetrahedron Letters · 1982 · 19 citations

Life Sciences, Biochemistry, Lipid Biochemistry +8

An approach to the preparation of glycosyl phosphates using salicylchlorophosphite as the phosphitylating reagent

J. P. G. Hermans, Erik de Vroom, C. J. J. Elie et al. · Recueil des Travaux Chimiques des Pays-Bas · 1986 · 18 citations

Pharmacy, Medicinal Chemistry, Synthetic Medicinal Chemistry +1