Mark C. de Gooijer

ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy

Fan Lin, Mark C. de Gooijer, Eloy Moreno Roig et al. · Clinical Cancer Research · 2014 · 145 citations

Medicine, Oncology, Pharmacology +16

Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2

Mark C. de Gooijer, Nienke A. de Vries, Tessa Buckle et al. · Neoplasia · 2018 · 135 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants

Abhijeet Pataskar, Julien Champagne, Remco Nagel et al. · Nature · 2022 · 135 citations · Full text

Life Sciences, Biochemistry, Immunology +16

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8

Jordi Berenguer, Tonny Lagerweij, Xi Zhao et al. · Journal of Extracellular Vesicles · 2018 · 102 citations · Full text

Medicine, Oncology, Pharmacology +17

P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib

Mark C. de Gooijer, Ping Zhang, Nishita Thota et al. · Investigational New Drugs · 2015 · 85 citations

Medicine, Oncology, Pharmacology +16