Elma Mons

The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K

Elma Mons, Ineke D.C. Jansen, Jure Loboda et al. · Journal of the American Chemical Society · 2019 · 115 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15

A Comprehensive Guide for Assessing Covalent Inhibition in Enzymatic Assays Illustrated with Kinetic Simulations

Elma Mons, Sander Roet, Robbert Q. Kim et al. · Current Protocols · 2022 · 111 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Organocatalytic Enantioselective Pictet–Spengler Reactions for the Syntheses of 1-Substituted 1,2,3,4-Tetrahydroisoquinolines

Elma Mons, Martin J. Wanner, Steen Ingemann et al. · The Journal of Organic Chemistry · 2014 · 81 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Exploring the Versatility of the Covalent Thiol–Alkyne Reaction with Substituted Propargyl Warheads: A Deciding Role for the Cysteine Protease

Elma Mons, Robbert Q. Kim, Bjorn R. van Doodewaerd et al. · Journal of the American Chemical Society · 2021 · 69 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity

Emma van Groesen, Elma Mons, Ioli Kotsogianni et al. · Science Translational Medicine · 2024 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16