Ivanhoe K. H. Leung - Concepedia

Author

Ivanhoe K. H. Leung

Also Known As

I Leung, I. K. H. Leung, I.K.H. Leung, Ivanhoe K H Leung, Ivanhoe K. H. Leung, Ivanhoe K.H. Leung, Ivanhoe Leung, Ivanhoe K. H. Leung, Ivanhoe K.H. Leung, Leung, Ivanhoe K. H.

113

Publications

Citations

H-Index

Concepts

All Affiliations

University of Auckland University of Oxford Maurice Wilkins Centre Keele University Institute of Chemical Biology and Fundamental Medicine

About

Ivanhoe K. H. Leung is an author at University of Auckland specializing in biochemistry, medicine, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Biochemistry	19	28	2.1K
2	Medicine	18	23	1.9K
3	Natural Sciences	17	22	1.8K
4	Engineering	7	7	209
5	Health Sciences	2	2	39

Ivanhoe K. H. Leung

Publications

3.5K

Citations

H-Index

Page 1

	Year	Citations
The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases Rasheduzzaman Chowdhury, Kar Kheng Yeoh, Ya‐Min Tian, EMBO Reports Histone ModificationsChromatinBiochemistryNatural SciencesMedicine	2011	1K
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials Tzu‐Lan Yeh, T.M. Leissing, Martine I. Abboud, Chemical Science	2017	219
Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases Nathan R. Rose, Esther C. Y. Woon, Anthony Tumber, Journal of Medicinal Chemistry Histone ModificationsEpigenetic ChangeChemical BiologyEnzymatic ModificationRedox Biology	2012	148
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases Rasheduzzaman Chowdhury, Ivanhoe K. H. Leung, Ya‐Min Tian, Nature Communications	2016	145
Structural and Mechanistic Studies on γ-Butyrobetaine Hydroxylase Ivanhoe K. H. Leung, T. Krojer, Grazyna Kochan, Chemistry & Biology γ-Butyrobetaine HydroxylaseBiochemistryEnzyme CatalysisStructure-function Enzyme KineticsEnzymatic Modification	2010	99
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors Marina Demetriades, Ivanhoe K. H. Leung, Rasheduzzaman Chowdhury, Angewandte Chemie International Edition Combinatorial ChemistryOrganic ChemistryChemistryPotent Oxygenase InhibitorsBorophene	2012	87
Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models Olga A. Luzina, D. N. Sokolov, Jinal Patel, European Journal of Medicinal Chemistry Vivo Tumor ModelsTherapeutic ImpactMedicineTumor TargetingAnti-cancer Agent	2018	79
Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases Hanna Tarhonskaya, Anna M. Rydzik, Ivanhoe K. H. Leung, Nature Communications Cellular EnzymologyBiochemistryMedicineRedox BiologyOxidative Stress	2014	78
Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation John S. Scotti, Ivanhoe K. H. Leung, Wei Ge, Proceedings of the National Academy of Sciences	2014	68
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain Mun Chiang Chan, Onur Atasoylu, Emma J. Hodson, PLoS ONE Murine BrainPharmacotherapyHypoxia-inducible Factor Prolyl-hydroxylasesRedox BiologyOxidative Stress	2015	65

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