Esther C. Y. Woon

The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

Rasheduzzaman Chowdhury, Kar Kheng Yeoh, Ya‐Min Tian et al. · EMBO Reports · 2011 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

A safe lithium mimetic for bipolar disorder

Nisha Singh, Amy C. Halliday, Justyn M. Thomas et al. · Nature Communications · 2013 · 257 citations · Full text

Medicine, Pharmacology, Psychiatry +12

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

Nathan R. Rose, Esther C. Y. Woon, Anthony Tumber et al. · Journal of Medicinal Chemistry · 2012 · 159 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5

Shui Zou, Joel D. W. Toh, Kendra H. Q. Wong et al. · Scientific Reports · 2016 · 159 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches

Nathan R. Rose, Esther C. Y. Woon, Guy L. Kingham et al. · Journal of Medicinal Chemistry · 2010 · 148 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17