CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH‐associated neurodegeneration and mass lesions

Kenneth L. McClain, Jennifer Picarsic, Rikhia Chakraborty, +41

Cancer

RAF/MEK/extracellular signal–related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions

Brandon Hogstad, Marie‐Luise Berres, Rikhia Chakraborty, +21

The Journal of Experimental Medicine

BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology

Camille Bigenwald, Jessica Le Bérichel, C. Matthias Wilk, +24

Nature Medicine

Cell SignalingHistiocytosis PathophysiologyAutophagyCell DeathCellular Senescence +4

IFN-γ signature in the plasma proteome distinguishes pediatric hemophagocytic lymphohistiocytosis from sepsis and SIRS

Howard Lin, Brooks Scull, Baruch R. Goldberg, +28

Blood Advances

ImmunohematologySevere SepsisImmunodeficienciesImmune RegulationImmunology +28

Salt Sensitivity and the Activities of the H+‐ATPases in Cotton Seedlings

Howard Lin, Sandra S. Salus, Karen S. Schumaker

Crop Science

BiologySalt StressSalt SensitivityOsmotic StressPlant Stress +10

Circulating CD1c+ myeloid dendritic cells are potential precursors to LCH lesion CD1a+CD207+ cells

Karen Phaik Har Lim, Paul Milne, Michael Poidinger, +17

Blood Advances

Hematological MalignancyImmunogeneticsAutoimmune DiseaseMedicineBrafv600e Allele +13

Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders

C. Matthias Wilk, Flurin Cathomas, Orsolya Török, +27

Immunity

Neurodegenerative DiseasesMedicineImmunologyHematologyBrain-immune Interaction +11

Clofarabine monotherapy in aggressive, relapsed and refractory Langerhans cell histiocytosis

Deevyashali Parekh, Howard Lin, Akanksha Batajoo, +28

British Journal of Haematology

Inferior Vena Cava Diameter is an Early Marker of Central Hypovolemia during Simulated Blood Loss

Blair D. Johnson, Zachary J. Schlader, Michael W. Schaake, +7

Prehospital Emergency Care

Clinical, radiological and molecular responses to combination chemotherapy with <scp>MAPK</scp> pathway inhibition in relapsed and refractory Langerhans cell histiocytosis

Vivekanudeep Karri, Howard Lin, Jessica Velazquez, +14

British Journal of Haematology