Dwight V. Nissley

Undermining Glutaminolysis Bolsters Chemotherapy While NRF2 Promotes Chemoresistance in KRAS-Driven Pancreatic Cancers

Suman Mukhopadhyay, Debanjan Goswami, Pavan P. Adiseshaiah et al. · Cancer Research · 2020 · 315 citations · Full text

Medicine, Cancer Biology, Oncology +17

ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications

Ming Yi, Dwight V. Nissley, Frank McCormick et al. · Scientific Reports · 2020 · 255 citations · Full text

Life Sciences, Bioinformatics, Oncology +17

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation

Timothy H. Tran, Albert H. Chan, Lucy C. Young et al. · Nature Communications · 2021 · 252 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Sensitive Drug‐Resistance Assays Reveal Long‐Term Persistence of HIV‐1 Variants with the K103N Nevirapine (NVP) Resistance Mutation in Some Women and Infants after the Administration of Single‐Dose NVP: HIVNET 012

Tamara Flys, Dwight V. Nissley, Cassidy W. Claasen et al. · The Journal of Infectious Diseases · 2005 · 190 citations · Full text

Life Sciences, Pharmacology, Pharmacotherapy +17

Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ

Srisathiyanarayanan Dharmaiah, Lakshman Bindu, Timothy H. Tran et al. · Proceedings of the National Academy of Sciences · 2016 · 176 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17