Charles P. Najt

Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis

Charles P. Najt, S. Subramanian, Mohammad B. Aljazi et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2016 · 150 citations · Full text

Diet-induced Hepatic Steatosis, Lipid Peroxidation, Immunology +24

Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1

Charles P. Najt, Salmaan Khan, Timothy D. Heden et al. · Molecular Cell · 2019 · 150 citations · Full text

Lipid Synthesis, Biochemistry, Allosterically Activate Sirt1 +3

Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism

Charles P. Najt, Santosh Adhikari, Timothy D. Heden et al. · Cell Reports · 2023 · 64 citations · Full text

Mitochondrial Biology, Fatty Liver Disease, Numerous Organelles +19

Structural and Functional Assessment of Perilipin 2 Lipid Binding Domain(s)

Charles P. Najt, Joel Lwande, Avery L. McIntosh et al. · Biochemistry · 2014 · 55 citations · Full text

Hepatic PLIN5 signals via SIRT1 to promote autophagy and prevent inflammation during fasting

Enxiang Zhang, Wenqi Cui, Michael Lopresti et al. · Journal of Lipid Research · 2020 · 54 citations · Full text