Chemically defined generation of human cardiomyocytes

Paul W. Burridge, Elena Matsa, Praveen Shukla, +12

Nature Methods

Regenerative MedicineCardiac MuscleCardiomyopathyMolecular PhysiologyCardiac Reprogramming +10

Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

Paul W. Burridge, Yong Fuga Li, Elena Matsa, +14

Nature Medicine

Doxorubicin-induced CardiotoxicityInduced Pluripotent Stem CellBreast OncologyOncologyCardiac Reprogramming +12

Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells

Feng Lan, Andrew S. Lee, Ping Liang, +21

Cell stem cell

Cardiac MuscleCardiomyopathyHeart FailureDevelopmental BiologyInduced Pluripotent Stem Cell +6

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model

Johannes Riegler, Malte Tiburcy, Antje Ebert, +15

Circulation Research

Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell–Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome

Ping Liang, Karim Sallam, Haodi Wu, +19

Journal of the American College of Cardiology

CardiomyopathyInduced Pluripotent Stem CellCardiac ReprogrammingMedicineGenetics +6

iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy

Kazuki Kodo, Sang-Ging Ong, Fereshteh Jahanbani, +14

Nature Cell Biology

Abnormal Tgf-β SignallingCardiac MuscleHeart FailureMolecular PhysiologySignal Transduction +11

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance

Patricia E. de Almeida, Everett Meyer, Nigel G. Kooreman, +13

Nature Communications

Regenerative MedicineCell TherapyInduced Pluripotent Stem CellTransplantationMedicine +11

Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns

Verónica Sánchez-Freire, Antje Ebert, Tomer Kalisky, +2

Nature Protocols

EngineeringReal-time Polymerase Chain ReactionGene Expression ProfilingSingle Cell SequencingComparative Analysis +14

Paracrine Effects of the Pluripotent Stem Cell-Derived Cardiac Myocytes Salvage the Injured Myocardium

Atsushi Tachibana, Michelle Santoso, Morteza Mahmoudi, +10

Circulation Research

Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes as an In Vitro Model for Coxsackievirus B3–Induced Myocarditis and Antiviral Drug Screening Platform

Arun Sharma, Caleb Marceau, Ryoko Hamaguchi, +15

Circulation Research