Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell–Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome

Right bundle branch block, persistent ST segment elevation and sudden cardiac death: A distinct clinical and electrocardiographic syndrome

Pedro Brugada, Josép Brugada · Journal of the American College of Cardiology · 1992 · 3.3K citations

Medicine, Cardiology, Clinical Cardiology +15

Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

Qiuyun Chen, Glenn E. Kirsch, Danmei Zhang et al. · Nature · 1998 · 1.8K citations

Medicine, Cardiology, Genetics +16

Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

Xiaojun Lian, Cheston Hsiao, Gisela F. Wilson et al. · Proceedings of the National Academy of Sciences · 2012 · 1.8K citations · Full text

Life Sciences, Cardiology, Developmental Biology +17

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

Noemi Fusaki, Hiroshi Ban, Akiyo Nishiyama et al. · Proceedings of the Japan Academy Series B · 2009 · 1.4K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +14

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

Alessandra Moretti, Milena Bellin, Andrea Welling et al. · New England Journal of Medicine · 2010 · 1.2K citations · Full text

Medicine, Cardiology, Genetics +17