Jessica E. Young

Somatic coding mutations in human induced pluripotent stem cells

Athurva Gore, Zhe Li, Ho-Lim Fung et al. · Nature · 2011 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Inhibition of Calpain Cleavage of Huntingtin Reduces Toxicity

Juliette Gafni, Evan Hermel, Jessica E. Young et al. · Journal of Biological Chemistry · 2004 · 285 citations · Full text

Life Sciences, Molecular Biology, Neurobiology +17

Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

Evan Hermel, Juliette Gafni, Stephanie Propp et al. · Cell Death and Differentiation · 2004 · 222 citations

Life Sciences, Neurobiology, Neuroscience +13

Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells

Jessica E. Young, Jonathan Boulanger-Weill, Daniel A. Williams et al. · Cell stem cell · 2015 · 191 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells

Grace Woodruff, Jessica E. Young, Fernando J. Martínez et al. · Cell Reports · 2013 · 183 citations · Full text

Life Sciences, Genetics, Neuroscience +17