Jessica E. Young

Somatic coding mutations in human induced pluripotent stem cells

Athurva Gore, Zhe Li, Ho-Lim Fung et al. · Nature · 2011 · 1.2K citations · Full text

Inhibition of Calpain Cleavage of Huntingtin Reduces Toxicity

Juliette Gafni, Evan Hermel, Jessica E. Young et al. · Journal of Biological Chemistry · 2004 · 284 citations · Full text

Calpain Cleavage, Cell Death, Cellular Physiology +16

Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

Evan Hermel, Juliette Gafni, Stephanie Propp et al. · Cell Death and Differentiation · 2004 · 221 citations · Full text

Specific Caspase Interactions, Selective Neuronal Vulnerability, Neurochemical Biomarkers +5

The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells

Grace Woodruff, Jessica E. Young, Fernando J. Martínez et al. · Cell Reports · 2013 · 182 citations · Full text

Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells

Jessica E. Young, Jonathan Boulanger-Weill, Daniel A. Williams et al. · Cell stem cell · 2015 · 174 citations · Full text

Neurodegenerative Diseases, Induced Pluripotent Stem Cell, Alzheimer's Disease +9