Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

Blue B. Lake, Rizi Ai, Gwendolyn E. Kaeser, +18

Science

Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA

Shicheng Guo, Dinh Diep, Nongluk Plongthongkum, +3

Nature Genetics

ChromatinDna SequencingPlasma DnaHeterogeneous Tissue SamplesMedicine +9

Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics

Li Shen, Hao Wu, Dinh Diep, +5

Cell

ChromatinChromatin RemodelingEpigenetic ChangeDna MethylationEpigenomics +3

Massively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells

Jeff Gole, Athurva Gore, Andrew Richards, +7

Nature Biotechnology

EngineeringNanoliter MicrowellsSingle Cell SequencingMedicineBiotechnology +6

Human oocytes reprogram somatic cells to a pluripotent state

Scott Noggle, Ho-Lim Fung, Athurva Gore, +13

Nature

OocyteInduced Pluripotent Stem CellStem Cell ResearchPluripotent StateMedicine +1

Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs

Guang‐Hui Liu, Keiichiro Suzuki, Jing Qu, +15

Cell stem cell

Genetic DisorderGeneticsGene CorrectionPathologyMolecular Genetics +5

Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells

Sergio Ruiz, Dinh Diep, Athurva Gore, +14

Proceedings of the National Academy of Sciences

Epigenetic ChangeGeneticsEpigeneticsPluripotent Stem CellsMolecular Epigenetics +15

Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy

Sara E. Howden, Athurva Gore, Zhe Li, +13

Proceedings of the National Academy of Sciences

Library-free methylation sequencing with bisulfite padlock probes

Dinh Diep, Nongluk Plongthongkum, Athurva Gore, +3

Nature Methods

Long-read SequencingDna SequencingMolecular BiologyGenomicsBisulfite Padlock Probes +3

Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming

Sergio Ruiz, Athurva Gore, Zhe Li, +10

Nature Communications

Genome InstabilitySomatic VariantSomatic Cell GeneticsMedicineGenetics +8