Robert A. Kumpf

A Mechanism for Ion Selectivity in Potassium Channels: Computational Studies of Cation-π Interactions

Robert A. Kumpf, Dennis A. Dougherty · Science · 1993 · 636 citations

Anticancer Chemosensitization and Radiosensitization by the Novel Poly(ADP-ribose) Polymerase-1 Inhibitor AG14361

Christopher Calabrese, Robert J. Almassy, Stephen Barton et al. · JNCI Journal of the National Cancer Institute · 2004 · 482 citations · Full text

Molecular recognition in aqueous media. New binding studies provide further insights into the cation-.pi. interaction and related phenomena

Patrick C. Kearney, Laura S. Mizoue, Robert A. Kumpf et al. · Journal of the American Chemical Society · 1993 · 274 citations

Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity:  Design, Synthesis, and X-ray Cocrystal Structure

Stacie S. Canan Koch, Lars Thoresen, Jayashree Tikhe et al. · Journal of Medicinal Chemistry · 2002 · 134 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Parp-1 Protein +18

Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (<i>R</i>)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2<i>H</i>)-one (PF-06821497)

Pei‐Pei Kung, Patrick Bingham, Alexei Brooun et al. · Journal of Medicinal Chemistry · 2017 · 125 citations · Full text