Crystal N. Doty

Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin

Rona K. Graham, Yu Deng, Elizabeth Slow et al. · Cell · 2006 · 649 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +15

Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin

Jeffrey B. Carroll, Simon C. Warby, Amber L. Southwell et al. · Molecular Therapy · 2011 · 292 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

HTT haplotypes contribute to differences in Huntington disease prevalence between Europe and East Asia

Simon C. Warby, Henk Visscher, Jennifer A. Collins et al. · European Journal of Human Genetics · 2011 · 165 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

Michael E. Østergaard, Amber L. Southwell, Holly Kordasiewicz et al. · Nucleic Acids Research · 2013 · 162 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Amber L. Southwell, Niels H. Skotte, Holly Kordasiewicz et al. · Molecular Therapy · 2014 · 148 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17