Crystal N. Doty

Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin

Rona K. Graham, Yu Deng, Elizabeth Slow et al. · Cell · 2006 · 646 citations · Full text

Neurodegenerative Diseases, Developmental Biology, Molecular Neuroscience +10

Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin

Jeffrey B. Carroll, Simon C. Warby, Amber L. Southwell et al. · Molecular Therapy · 2011 · 287 citations · Full text

HTT haplotypes contribute to differences in Huntington disease prevalence between Europe and East Asia

Simon C. Warby, Henk Visscher, Jennifer A. Collins et al. · European Journal of Human Genetics · 2011 · 164 citations · Full text

Huntington Disease Prevalence, Haplotype Determination, Genetic Disorder +9

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

Michael E. Østergaard, Amber L. Southwell, Holly Kordasiewicz et al. · Nucleic Acids Research · 2013 · 158 citations · Full text

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Amber L. Southwell, Niels H. Skotte, Holly Kordasiewicz et al. · Molecular Therapy · 2014 · 145 citations · Full text