Concepedia

Xufen Yu

XY

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Publications

42

Citations

2.1K

H-Index

27

Active since

2009

Affiliations

Icahn School of Medicine at Mount Sinai(Current)

University of North Carolina at Chapel Hill

Chinese Academy of Sciences

Shanghai Institute of Organic Chemistry

University of Hawaii at Hilo

Xufen Yu is an author at Icahn School of Medicine at Mount Sinai specializing in medicine, natural sciences, and cell biology.

ORCID

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Publications per year

2009–2024

42

Publications

42

Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism

Alex J. Bott, Jianliang Shen, Claudia Tonelli et al. · Cell Reports · 2019 · 185 citations · Full text

EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis

Jun Wang, Xufen Yu, Weida Gong et al. · Nature Cell Biology · 2022 · 176 citations · Full text

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Discovery of Potent and Selective Epidermal Growth Factor Receptor (EGFR) Bifunctional Small-Molecule Degraders

Meng Cheng, Xufen Yu, Kaylene Lu et al. · Journal of Medicinal Chemistry · 2020 · 172 citations · Full text

A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models

Xufen Yu, Dongxu Li, Jithesh Kottur et al. · Science Translational Medicine · 2021 · 149 citations · Full text

Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders

Yudao Shen, Guozhen Gao, Xufen Yu et al. · Journal of Medicinal Chemistry · 2020 · 89 citations · Full text

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