Jane Birtwistle

Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production

Farhat L. Khanim, Blair Merrick, H V Giles et al. · Blood Cancer Journal · 2011 · 83 citations · Full text

Apoptosis, Immunology, Cell Death +23

Human intrahepatic regulatory T cells are functional, require IL‐2 from effector cells for survival, and are susceptible to Fas ligand‐mediated apoptosis

Yung‐Yi Chen, Hannah C. Jeffery, Stuart Hunter et al. · Hepatology · 2016 · 83 citations · Full text

The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: Implications for leukemogenesis

Jane Birtwistle, Rachel E. Hayden, Farhat L. Khanim et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 2009 · 80 citations

Hematological Malignancy, Reductive Stress, Aldo-keto Reductase Akr1c3 +12

Combined Bezafibrate and Medroxyprogesterone Acetate: Potential Novel Therapy for Acute Myeloid Leukaemia

Farhat L. Khanim, Rachel E. Hayden, Jane Birtwistle et al. · PLoS ONE · 2009 · 72 citations · Full text

AKR1C Isoforms Represent a Novel Cellular Target for Jasmonates alongside Their Mitochondrial-Mediated Effects

Nicholas Davies, Rachel E. Hayden, Paul J. Simpson et al. · Cancer Research · 2009 · 61 citations