Nicholas Davies

ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells

Marwan Kwok, Nicholas Davies, Angelo Agathanggelou et al. · Blood · 2015 · 266 citations

BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks

Martin R. Higgs, John J. Reynolds, Alicja Winczura et al. · Molecular Cell · 2015 · 207 citations

Genome Instability, Stressed Replication Forks, Natural Sciences +6

Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohort

Gabrielle L. Davidson, Sinéad M. Murphy, James M. Polke et al. · Journal of Neurology · 2012 · 101 citations

Mendelian Disorder, Genetic Disorder, Uk Cohort +13

Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway

Marwan Kwok, Nicholas Davies, Angelo Agathanggelou et al. · The Lancet · 2015 · 81 citations

Hematological Malignancy, Chronic Lymphocytic Leukaemia, Oncogenic Agent +10

The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: Implications for leukemogenesis

Jane Birtwistle, Rachel E. Hayden, Farhat L. Khanim et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 2009 · 80 citations

Hematological Malignancy, Reductive Stress, Aldo-keto Reductase Akr1c3 +12