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Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway

Hematological MalignancyChronic Lymphocytic LeukaemiaOncogenic AgentMixed-phenotype Acute LeukemiaMalignant Blood DisorderImmunologyCell DeathAdult T-cell Leukemia-lymphomaSynthetic LethalityMedicineCell BiologyGenome EditingAtr Pathway