Ole Niewoehner

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

Carolin Anders, Ole Niewoehner, A. Duerst et al. · Nature · 2014 · 1.4K citations

Life Sciences, Genetics, Molecular Biology +13

Type III CRISPR–Cas systems produce cyclic oligoadenylate second messengers

Ole Niewoehner, Carmela Garcia‐Doval, Jakob T. Rostøl et al. · Nature · 2017 · 505 citations

Life Sciences, Molecular Biology, Molecular Genetics +10

Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6

Ole Niewoehner, Martin Jínek · RNA · 2016 · 148 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6

Carmela Garcia‐Doval, Frank Schwede, Christian Berk et al. · Nature Communications · 2020 · 102 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases

Ole Niewoehner, Martin Jínek, Jennifer A. Doudna · Nucleic Acids Research · 2013 · 88 citations · Full text

Life Sciences, Microbiology, Molecular Biology +15