Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg ²⁺ Resorption

David B. Simon, Yin Lu, Keith A. Choate, +11

Science

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

Su'e Chang, Stefan Gründer, Aaron Hanukoglu, +9

Nature Genetics

Hyperkalaemic AcidosisElectrolyte DisorderMolecular PhysiologyBiochemistrySodium Homeostasis +6

Hypertension caused by a truncated epithelial sodium channel γ subunit: genetic heterogeneity of Liddle syndrome

Joni H. Hansson, Carol Nelson‐Williams, Hiroshi Suzuki, +7

Nature Genetics

HypertensionSodium HomeostasisGeneticsPhysiologyGenetic Epidemiology +4

Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.

Laurent Schild, Yin Lu, Ivan Gautschi, +3

The EMBO Journal

ChannelopathiesMolecular PhysiologySignal TransductionSignaling PathwayLiddle Syndrome +9

A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity.

Joni H. Hansson, Laurent Schild, Yin Lu, +6

Proceedings of the National Academy of Sciences

Liddle SyndromeMolecular BiologyCytoskeletonChannel SubunitsCellular Physiology +15

Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule

Maria D. Lalioti, Junhui Zhang, Heather M. Volkman, +10

Nature Genetics

HypertensionMolecular PhysiologySignal TransductionSodium HomeostasisCell Signaling +5

Correlation and agreement: overview and clarification of competing concepts and measures.

Jinyuan Liu, Wan Tang, Guanqin Chen, +3

PubMed

ReliabilityQuantitative PsychologyPearson CorrelationCognitive ScienceIntraclass Correlation +11

Mitotic Recombination in Patients with Ichthyosis Causes Reversion of Dominant Mutations in <i>KRT10</i>

Keith A. Choate, Yin Lu, Jing Zhou, +10

Science

GeneticsPathologyMolecular GeneticsDermatologyEpigenetics +16

The genome-wide role of HSF-1 in the regulation of gene expression in Caenorhabditis elegans

Jessica Brunquell, Stephanie A. Morris, Yin Lu, +2

BMC Genomics

SHP2 inhibition triggers anti-tumor immunity and synergizes with PD-1 blockade

Mingxia Zhao, Wenjie Guo, Yuanyuan Wu, +11

Acta Pharmaceutica Sinica B